When I go out of town, I always have a pet sitter watch my critters, as opposed to kenneling them. To me, there is no question as to which option is best for my dogs and cats. They can remain at home with familiar smells and best of all, each other to curl up with at night.
I am luckier than most; I have a cousin who loves my animals, and insists on staying at my house with them when I’m out of town! It doesn’t get much better than that. I have absolutely nothing to worry about; she even holds up the phone to them when I call and lets them hear my voice! Rather than upsetting them, it seem to give them comfort.
I know not everyone has this option, but if you can work out a way for your companions to remain at home when you can’t, I advise it strongly!